Zepbound Availability and Pricing at Costco: What You Need to Know

Understanding Zepbound

Zepbound is a pharmaceutical product developed by Eli Lilly, aimed at aiding chronic weight management. It functions by targeting specific receptors in the body, namely the GIP and GLP-1 receptors. These receptors play a crucial role in regulating insulin and glucagon, hormones that are integral to glucose metabolism and appetite control. By acting on these receptors, Zepbound helps to manage weight more effectively when combined with lifestyle changes such as a reduced-calorie diet and increased physical activity.

Zepbound's Market Position

Eli Lilly's Zepbound competes directly with Novo Nordisk's popular weight loss medications, Ozempic and Wegovy. While Ozempic and Wegovy are available at Costco pharmacies for $499 for self-pay customers, Zepbound's pricing is notably higher. The out-of-pocket cost for Zepbound at Costco is reported to be between $1090 and $1120 per box. This price range reflects its specialized formulation and the competitive landscape of weight management drugs.

Pricing and Discounts at Costco

Costco pharmacies are known for their competitive pricing strategies, particularly for prescription medications. For Ozempic and Wegovy, Costco offers these drugs at about half and two-thirds less than their respective list prices. Additionally, executive members and Costco Citibank Visa card holders can benefit from an extra 2% discount on these medications. However, similar discount details for Zepbound have not been specified, suggesting that its pricing strategy might differ from that of its competitors.

Availability at Costco

Costco pharmacies have a widespread presence, with over 500 locations across the United States offering prescription-only injectable pens for Ozempic and Wegovy. While Zepbound is also available at Costco, its higher price point may influence consumer choice. The availability of these medications at Costco provides consumers with convenient access to weight management solutions, although the cost differences may impact purchasing decisions.

Conclusion

Zepbound represents a significant option in the realm of chronic weight management medications, offering a unique mechanism of action through its GIP and GLP-1 receptor agonism. While its pricing at Costco is higher compared to competitors like Ozempic and Wegovy, its specialized formulation and market positioning by Eli Lilly underscore its value. As consumers navigate their options, the availability of these medications at Costco provides a convenient and potentially cost-effective solution for those seeking to manage their weight effectively.

FAQs

**Is Zepbound available at all Costco locations?**
Zepbound is available at Costco pharmacies, which have over 500 locations in the United States, although specific availability may vary by location.

**How does Zepbound compare in price to Ozempic and Wegovy at Costco?**
Zepbound is priced between $1090 and $1120 per box at Costco, which is significantly higher than the $499 price for Ozempic and Wegovy for self-pay customers.

**Are there any discounts available for Zepbound at Costco?**
While Costco offers a 2% discount on Ozempic and Wegovy for executive members and Costco Citibank Visa card holders, specific discount details for Zepbound have not been provided.

References

https://www.costco.com/cmpps?drugIdentifierParam=55557705156&drugNameParam=Zepbound
https://www.usatoday.com/story/news/health/2025/10/06/costco-pharmacy-weight-loss-drugs-ozempic-wegovy/86551684007/
https://www.today.com/health/news/costco-weight-loss-drugs-rcna235425
https://www.reddit.com/r/Zepbound/comments/1ejd3sc/out_of_pocket_cost_at_costco/
https://www.nytimes.com/2025/10/05/health/ozempic-wegovy-costco.html
https://www.goodrx.com/zepbound
https://www.nbcnews.com/health/health-news/costco-ozempic-wegovy-discount-insurance-rcna235471
https://www.oprahdaily.com/life/health/a68850863/costco-ozempic-wegovy-discount/